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Lillestol Research has several years of trial experience in the osteoarthritis (OA) indication/diagnosis, including both OA of the knee and the hip. The trials have varied in phase, enrollment criteria, and duration. The multitude of trials that we have performed in this indication has developed a robust research patient database presenting nearly 2,000 patients with an OA diagnosis that would be interested in clinical trial participation.

Spotlight Trial(s)

  1. This was a long-term investigational product, placebo-controlled trial evaluating oral IP in patients with symptomatic osteoarthritis of the knee. Lillestol Research was able to successfully meet and far exceed the sponsor’s enrollment expectation randomizing 32 patients to the trial.
  2. This was an investigational product, placebo-controlled trial evaluating effectiveness of IP in patients with symptomatic osteoarthritis of the knee. Lillestol Research was an add-on site and impressed the trial sponsor in our ability to successfully meet and exceed the enrollment expectation randomizing 8 patients to the trial in only 2 months of enrollment. A credit to our excellent patient retention rates, 7 of our 8 randomized patients continued on to participate in a long-term extension trial after completing the core trial.


Osteoarthritis is the most common form of arthritis, affecting millions of people worldwide. It occurs when the protective cartilage on the ends of your bones wears down over time.

Although osteoarthritis can damage any joint in your body, the disorder most commonly affects joints in your hands, knees, hips and spine.

Osteoarthritis often gradually worsens, and no cure exists. But staying active, maintaining a healthy weight and other treatments may slow progression of the disease and help improve pain and joint function.


Osteoarthritis symptoms often develop slowly and worsen over time. Signs and symptoms of osteoarthritis include:

  • Pain. Your joint may hurt during or after movement.
  • Tenderness. Your joint may feel tender when you apply light pressure to it.
  • Stiffness. Joint stiffness may be most noticeable when you wake up in the morning or after a period of inactivity.
  • Loss of flexibility. You may not be able to move your joint through its full range of motion.
  • Grating sensation. You may hear or feel a grating sensation when you use the joint.
  • Bone spurs. These extra bits of bone, which feel like hard lumps, may form around the affected joint.



If you have been diagnosed or believe you have osteoarthritis of the knee contact us today to learn more about our current study opportunities for this diagnosis.

Call us at (701) 232-7705 or toll-free at (866) 532-7705

Signup online or email our recruiter at recruiter(at)lillestolresearch(dot)com.

Your information is always kept confidential.